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Caffeine-clozapine interaction associated with severe toxicity and multiorgan system failure: a case report

BACKGROUND: Caffeine is a known inhibitor of Clozapine metabolism mediated by inhibition of CYP1A2. Hitherto, the effects of caffeine on Clozapine levels have always been modest, as have the clinical manifestations of toxicity resulting from their interaction. We present a case of severe toxicity as...

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Vydáno v:BMC Psychiatry
Hlavní autoři: Yartsev, Alex, Peisah, Carmelle
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043221/
https://ncbi.nlm.nih.gov/pubmed/33849480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-021-03199-x
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