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Caffeine-clozapine interaction associated with severe toxicity and multiorgan system failure: a case report

BACKGROUND: Caffeine is a known inhibitor of Clozapine metabolism mediated by inhibition of CYP1A2. Hitherto, the effects of caffeine on Clozapine levels have always been modest, as have the clinical manifestations of toxicity resulting from their interaction. We present a case of severe toxicity as...

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Detalhes bibliográficos
Publicado no:BMC Psychiatry
Main Authors: Yartsev, Alex, Peisah, Carmelle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043221/
https://ncbi.nlm.nih.gov/pubmed/33849480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-021-03199-x
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