Ros3 (Lem3p/CDC50) Gene Dosage Is Implicated in Miltefosine Susceptibility in Leishmania (Viannia) braziliensis Clinical Isolates and in Leishmania (Leishmania) major

[Image: see text] The Ros3 protein is a component of the MT-Ros3 transporter complex, considered as the main route of miltefosine entry in Leishmania. L. braziliensis clinical isolates presenting differences in miltefosine susceptibility and uptake were previously shown to differentially express ros...

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Vydáno v:ACS Infect Dis
Hlavní autoři: Espada, Caroline R., Albuquerque-Wendt, Andreia, Hornillos, Valentín, Gluenz, Eva, Coelho, Adriano C., Uliana, Silvia R. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2021
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042657/
https://ncbi.nlm.nih.gov/pubmed/33724800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00857
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