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Binary surrogate endpoints in clinical trials from the perspective of case definitions

INTRODUCTION: Surrogate endpoints are widely used in clinical trials, especially in situations where the endpoint of interest is not directly observable or to avoid long trial periods. A typical example for this case is frequently found in clinical trials in oncology, where overall survival (OS) as...

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Bibliografski detalji
Izdano u:Eur J Microbiol Immunol (Bp)
Glavni autori: HAHN, ANDREAS, PODBIELSKI, ANDREAS, HEIMESAAT, MARKUS M., FRICKMANN, HAGEN, WARNKE, PHILIPP
Format: Artigo
Jezik:Inglês
Izdano: Akadémiai Kiadó 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042653/
https://ncbi.nlm.nih.gov/pubmed/33666567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/1886.2020.00031
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