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Stoichiometry of multi-specific immune checkpoint RNA Abs for T cell activation and tumor inhibition using ultra-stable RNA nanoparticles

Immunotherapy has become a revolutionary subject in cancer therapy during the past few years. Immune checkpoint-targeting antibodies (Abs) could boost anticancer immune responses. However, certain protein-based immunotherapies revealed side effects and unfavorable biodistribution, so effective non-p...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Shu, Dan, Zhang, Long, Bai, Xuefeng, Yu, Jianhua, Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042240/
https://ncbi.nlm.nih.gov/pubmed/33868786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.03.007
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