The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones

The sensitivity of the protein-folding environment to chaperone disruption can be highly tissue-specific. Yet, the organization of the chaperone system across physiological human tissues has received little attention. Through computational analyses of large-scale tissue transcriptomes, we unveil tha...

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Udgivet i:Nat Commun
Main Authors: Shemesh, Netta, Jubran, Juman, Dror, Shiran, Simonovsky, Eyal, Basha, Omer, Argov, Chanan, Hekselman, Idan, Abu-Qarn, Mehtap, Vinogradov, Ekaterina, Mauer, Omry, Tiago, Tatiana, Carra, Serena, Ben-Zvi, Anat, Yeger-Lotem, Esti
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042005/
https://ncbi.nlm.nih.gov/pubmed/33846299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22369-9
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