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Multisubstituted pyrimidines effectively inhibit bacterial growth and biofilm formation of Staphylococcus aureus

Biofilms are multicellular communities of microorganisms that generally attach to surfaces in a self-produced matrix. Unlike planktonic cells, biofilms can withstand conventional antibiotics, causing significant challenges in the healthcare system. Currently, new chemical entities are urgently neede...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Provenzani, Riccardo, San-Martin-Galindo, Paola, Hassan, Ghada, Legehar, Ashenafi, Kallio, Aleksi, Xhaard, Henri, Fallarero, Adyary, Yli-Kauhaluoma, Jari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041844/
https://ncbi.nlm.nih.gov/pubmed/33846401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86852-5
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