The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells

Endoplasmic reticulum (ER) stress plays an important role in hepatocyte degeneration, especially in patients with chronic liver injury. Protein kinase R-like endoplasmic reticulum kinase (PERK) is a key molecule in ER stress. PERK may contribute to apoptotic cell death in HCC, however the details of...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yukimoto, Atsushi, Watanabe, Takao, Sunago, Kotaro, Nakamura, Yoshiko, Tanaka, Takaaki, Koizumi, Yohei, Yoshida, Osamu, Tokumoto, Yoshio, Hirooka, Masashi, Abe, Masanori, Hiasa, Yoichi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041825/
https://ncbi.nlm.nih.gov/pubmed/33846370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86592-6
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