The FCGR3A 158 V/V-genotype is associated with decreased survival of renal allografts with chronic active antibody-mediated rejection

Natural killer (NK) cells express the Fc-gamma receptor CD16 (FCGR3A) and could therefore mediate renal endothelial cell damage in cases of chronic-active antibody mediated rejection (c-aABMR). The V/V-genotype of the FCGR3A 158 F/V polymorphism is associated with increased CD16 expression and cytot...

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Publicado en:Sci Rep
Autores principales: Litjens, Nicolle, Peeters, Annemiek, Gestel, Judith Kal-van, Klepper, Mariska, Betjes, Michiel
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041758/
https://ncbi.nlm.nih.gov/pubmed/33846428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86943-3
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