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One Plus One Makes Three: Triangular Coupling of Correlated Amino Acid Mutations

[Image: see text] Correlated mutations have played a pivotal role in the recent success in protein fold prediction. Understanding nonadditive effects of mutations is crucial for altering protein structure, as mutations of multiple residues may change protein stability or binding affinity in a manner...

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Publicat a:J Phys Chem Lett
Autors principals: Werner, Martin, Gapsys, Vytautas, de Groot, Bert L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041375/
https://ncbi.nlm.nih.gov/pubmed/33760609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.1c00380
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