A Pd-Catalyzed [4 + 2] Annulation Approach to Fluorinated N-Heterocycles

[Image: see text] 3-Fluoro- and trifluoromethylthio-piperidines represent important building blocks for discovery chemistry. We report a simple and efficient method to access analogs of these compounds that are armed with rich functionality allowing them to be chemoselectively derivatized with high...

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Détails bibliographiques
Publié dans:Org Lett
Auteurs principaux: García-Vázquez, Víctor, Hoteite, Larry, Lakeland, Christopher P., Watson, David W., Harrity, Joseph P. A.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041373/
https://ncbi.nlm.nih.gov/pubmed/33759534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.1c00752
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