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N-Heterocyclic Carbene Catalyzed Enantioselective Annulation of Benzothiazolyl Ethyl Acetates with 2-Bromoenals

An N-heterocyclic carbene catalyzed enantioselective [3+3] annulation of benzothiazolyl acetates with 2-bromoenals has been developed. The protocol provides a direct asymmetric synthesis of dihydro-1H-benzothiazolopyridinones in good to very good yields and medium ee values. In many cases, the virtu...

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Dades bibliogràfiques
Publicat a:Synlett
Autors principals: Ni, Qijian, Xiong, Jiawen, Song, Xiaoxiao, Raabe, Gerhard, Enders, Dieter
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702349/
https://ncbi.nlm.nih.gov/pubmed/26752810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0034-1381004
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