Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain

The folate and methionine cycles, constituting one-carbon metabolism, are critical pathways for cell survival. Intersecting these two cycles, 5,10-methylenetetrahydrofolate reductase (MTHFR) directs one-carbon units from the folate to methionine cycle, to be exclusively used for methionine and S-ade...

全面介紹

Na minha lista:
書目詳細資料
發表在:Biochimie
Main Authors: Bezerra, Gustavo A., Holenstein, Alexander, Foster, William R., Xie, Bing, Hicks, Kevin G., Bürer, Céline, Lutz, Seraina, Mukherjee, Ayan, Sarkar, Dipika, Bhattacharya, Debomita, Rutter, Jared, Talukdar, Arindam, Brown, Peter J., Luo, Minkui, Shi, Lei, Froese, D. Sean, Yue, Wyatt W.
格式: Artigo
語言:Inglês
出版: Editions Scientifiques Elsevier 2021
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040968/
https://ncbi.nlm.nih.gov/pubmed/33476699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2021.01.007
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍