A limited role of NKCC1 in telencephalic glutamatergic neurons for developing hippocampal network dynamics and behavior

NKCC1 is the primary transporter mediating chloride uptake in immature principal neurons, but its role in the development of in vivo network dynamics and cognitive abilities remains unknown. Here, we address the function of NKCC1 in developing mice using electrophysiological, optical, and behavioral...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Graf, Jürgen, Zhang, Chuanqiang, Marguet, Stephan Lawrence, Herrmann, Tanja, Flossmann, Tom, Hinsch, Robin, Rahmati, Vahid, Guenther, Madlen, Frahm, Christiane, Urbach, Anja, Neves, Ricardo Melo, Witte, Otto W., Kiebel, Stefan J., Isbrandt, Dirk, Hübner, Christian A., Holthoff, Knut, Kirmse, Knut
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040628/
https://ncbi.nlm.nih.gov/pubmed/33782119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014784118
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