Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition

BACKGROUND: Optogenetic silencing techniques have expanded the causal understanding of the functions of diverse neuronal cell types in both the healthy and diseased brain. A widely used inhibitory optogenetic actuator is eNpHR3.0, an improved version of the light-driven chloride pump halorhodopsin d...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Zhang, Chuanqiang, Yang, Shang, Flossmann, Tom, Gao, Shiqiang, Witte, Otto W., Nagel, Georg, Holthoff, Knut, Kirmse, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882325/
https://ncbi.nlm.nih.gov/pubmed/31775747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0717-6
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