MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism

Manganese superoxide dismutase (MnSOD) acetylation (Ac) has been shown to be a key post-translational modification important in the regulation of detoxification activity in various disease models. We have previously demonstrated that MnSOD lysine-68 (K68) acetylation (K68-Ac) leads to a change in fu...

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Bibliographic Details
Published in:Int J Biol Sci
Main Authors: Gao, Yucheng, Zhu, Yueming, Tran, Elizabeth L., Tokars, Valerie, Dean, Angela E., Quan, Songhua, Gius, David
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2021
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040469/
https://ncbi.nlm.nih.gov/pubmed/33867840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.51184
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