Preventing tumor progression to the bone by induced tumor-suppressing MSCs

Background: Advanced breast cancer metastasizes to many organs including bone, but few effective treatments are available. Here we report that induced tumor-suppressing (iTS) MSCs protected bone from metastases while un-induced MSCs did not. Methods: iTS MSCs were generated by overexpressing Lrp5, β...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Sun, Xun, Li, Kexin, Zha, Rongrong, Liu, Shengzhi, Fan, Yao, Wu, Di, Hase, Misato, Aryal, Uma K., Lin, Chien-Chi, Li, Bai-Yan, Yokota, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039940/
https://ncbi.nlm.nih.gov/pubmed/33859739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.58779
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