MicroRNA-223-3p inhibits vascular calcification and the osteogenic switch of vascular smooth muscle cells

Vascular calcification is the ectopic deposition of calcium hydroxyapatite minerals in arterial wall, which involves the transdifferentiation of vascular smooth muscle cells (VSMCs) toward an osteogenic phenotype. However, the underlying molecular mechanisms regulating the VSMC osteogenic switch rem...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Han, Yingchun, Zhang, Jichao, Huang, Shan, Cheng, Naixuan, Zhang, Congcong, Li, Yulin, Wang, Xiaonan, Liu, Jinghua, You, Bin, Du, Jie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039724/
https://ncbi.nlm.nih.gov/pubmed/33647318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100483
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