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MicroRNA-223-3p inhibits vascular calcification and the osteogenic switch of vascular smooth muscle cells

Vascular calcification is the ectopic deposition of calcium hydroxyapatite minerals in arterial wall, which involves the transdifferentiation of vascular smooth muscle cells (VSMCs) toward an osteogenic phenotype. However, the underlying molecular mechanisms regulating the VSMC osteogenic switch rem...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Han, Yingchun, Zhang, Jichao, Huang, Shan, Cheng, Naixuan, Zhang, Congcong, Li, Yulin, Wang, Xiaonan, Liu, Jinghua, You, Bin, Du, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039724/
https://ncbi.nlm.nih.gov/pubmed/33647318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100483
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