Germline and tumor BRCA1/2 mutations in Chinese high grade serous ovarian cancer patients

BACKGROUND: Studies on the prevalence of BRCA1/2 mutations in ovarian cancer mainly focused on germline single-nucleotide variant (SNV)/insertion/deletion (indel). The status of large genomic rearrangement (LRG) and somatic mutation were poorly investigated. METHODS: Paired blood and tumor DNA from...

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Detalles Bibliográficos
Publicado en:Ann Transl Med
Main Authors: Ji, Gang, Yao, Qianlan, Bao, Longlong, Zhang, Jing, Bai, Qianming, Zhu, Xiaoli, Tu, Xiaoyu, Bi, Rui, Zhou, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado: AME Publishing Company 2021
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039691/
https://ncbi.nlm.nih.gov/pubmed/33850850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-6827
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