Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary

BACKGROUND: Mounting evidence has shown that KRAS and BRAF are somatic mutations associated with low grade serous carcinoma (LGSC) of the ovary. However, the frequency of KRAS or BRAF mutation was variable in literatures, with a frequency of 16–54% for KRAS mutation and 2–33% for BRAF mutation. Mean...

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Detalles Bibliográficos
Publicado en:Diagn Pathol
Main Authors: Xu, Yan, Bi, Rui, Xiao, Yaoxing, Tu, Xiaoyu, Li, Ming, Li, Anqi, Shan, Ling, Zhou, Shuling, Yang, Wentao
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741942/
https://ncbi.nlm.nih.gov/pubmed/29273082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0679-3
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