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Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary

BACKGROUND: Mounting evidence has shown that KRAS and BRAF are somatic mutations associated with low grade serous carcinoma (LGSC) of the ovary. However, the frequency of KRAS or BRAF mutation was variable in literatures, with a frequency of 16–54% for KRAS mutation and 2–33% for BRAF mutation. Mean...

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Detalhes bibliográficos
Publicado no:Diagn Pathol
Main Authors: Xu, Yan, Bi, Rui, Xiao, Yaoxing, Tu, Xiaoyu, Li, Ming, Li, Anqi, Shan, Ling, Zhou, Shuling, Yang, Wentao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741942/
https://ncbi.nlm.nih.gov/pubmed/29273082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0679-3
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