Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary

BACKGROUND: Mounting evidence has shown that KRAS and BRAF are somatic mutations associated with low grade serous carcinoma (LGSC) of the ovary. However, the frequency of KRAS or BRAF mutation was variable in literatures, with a frequency of 16–54% for KRAS mutation and 2–33% for BRAF mutation. Mean...

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Dettagli Bibliografici
Pubblicato in:Diagn Pathol
Autori principali: Xu, Yan, Bi, Rui, Xiao, Yaoxing, Tu, Xiaoyu, Li, Ming, Li, Anqi, Shan, Ling, Zhou, Shuling, Yang, Wentao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741942/
https://ncbi.nlm.nih.gov/pubmed/29273082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0679-3
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