The Transferrin Receptor-Directed CAR for the Therapy of Hematologic Malignancies

As many patients ultimately relapse after chimeric antigen receptor (CAR) T-cell therapy, identification of alternative targets is currently being evaluated. Substantial research efforts are underway to develop new targets. The transferrin receptor (TfR) is prevalently expressed on rapidly prolifera...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Guo, Zilong, Zhang, Yirui, Fu, Mingpeng, Zhao, Liang, Wang, Zhen, Xu, Zhuoshuo, Zhu, Huifen, Lan, Xiaoli, Shen, Guanxin, He, Yong, Lei, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039461/
https://ncbi.nlm.nih.gov/pubmed/33854512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.652924
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