Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution

Gene regulatory divergence is thought to play a central role in determining human-specific traits. However, our ability to link divergent regulation to divergent phenotypes is limited. Here, we utilized human-chimpanzee hybrid induced pluripotent stem cells to study gene expression separating these...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Genet
Hlavní autoři: Gokhman, David, Agoglia, Rachel M., Kinnebrew, Maia, Gordon, Wei, Sun, Danqiong, Bajpai, Vivek K., Naqvi, Sahin, Chen, Coral, Chan, Anthony, Chen, Chider, Petrov, Dmitri A., Ahituv, Nadav, Zhang, Honghao, Mishina, Yuji, Wysocka, Joanna, Rohatgi, Rajat, Fraser, Hunter B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038968/
https://ncbi.nlm.nih.gov/pubmed/33731941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-021-00804-3
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky