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cis-Regulatory Mutations Are a Genetic Cause of Human Limb Malformations
The underlying mutations that cause human limb malformations are often difficult to determine, particularly for limb malformations that occur as isolated traits. Evidence from a variety of studies shows that cis-regulatory mutations, specifically in enhancers, can lead to some of these isolated limb...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174732/ https://ncbi.nlm.nih.gov/pubmed/21509892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22535 |
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