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Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the gene encoding the methyl-CpG-binding protein 2 (MeCP2). Among many different roles, MeCP2 has a high phenotypic impact during the different stages of brain development. Thus, it is essential to intensively investigate th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gomes, Ana Rita, Fernandes, Tiago G., Cabral, Joaquim M.S., Diogo, Maria Margarida
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038474/
https://ncbi.nlm.nih.gov/pubmed/33916879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073751
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