Modeling Rett Syndrome With Human Patient-Specific Forebrain Organoids

Engineering brain organoids from human induced pluripotent stem cells (hiPSCs) is a powerful tool for modeling brain development and neurological disorders. Rett syndrome (RTT), a rare neurodevelopmental disorder, can greatly benefit from this technology, since it affects multiple neuronal subtypes...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Gomes, Ana Rita, Fernandes, Tiago G., Vaz, Sandra H., Silva, Teresa P., Bekman, Evguenia P., Xapelli, Sara, Duarte, Sofia, Ghazvini, Mehrnaz, Gribnau, Joost, Muotri, Alysson R., Trujillo, Cleber A., Sebastião, Ana M., Cabral, Joaquim M. S., Diogo, Maria Margarida
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758289/
https://ncbi.nlm.nih.gov/pubmed/33363173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.610427
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