The human aortic endothelium undergoes dose-dependent DNA methylation in response to transient hyperglycemia.

BACKGROUND –: Glycemic control is a strong predictor of long-term cardiovascular risk in patients with diabetes mellitus, and poor glycemic control influences long-term risk of cardiovascular disease even decades after optimal medical management. This phenomenon, termed glycemic memory, has been pro...

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Bibliografiske detaljer
Udgivet i:Exp Cell Res
Main Authors: Pepin, Mark E., Schiano, Concetta, Miceli, Marco, Benincasa, Giuditta, Mansueto, Gelsomina, Grimaldi, Vincenzo, Soricelli, Andrea, Wende, Adam R., Napoli, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038422/
https://ncbi.nlm.nih.gov/pubmed/33515594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2021.112485
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