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Development of a Multimatrix UHPLC-MS/MS Method for the Determination of Paracetamol and Its Metabolites in Animal Tissues

Paracetamol/acetaminophen (APAP) is one of the most popular pharmacologically active substances used as an analgesic and antipyretic agent. The metabolism of this drug occurs in the liver and leads to the formation of two main metabolites—glucuronic acid and sulfate derivate. Despite the wide use of...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Pietruk, Konrad, Gbylik-Sikorska, Małgorzata, Łebkowska-Wieruszewska, Beata, Gajda, Anna, Giorgi, Mario, Sartini, Irene, Jedziniak, Piotr
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038326/
https://ncbi.nlm.nih.gov/pubmed/33918518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26072046
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