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In Silico Identification of Small Molecules as New Cdc25 Inhibitors through the Correlation between Chemosensitivity and Protein Expression Pattern

The cell division cycle 25 (Cdc25) protein family plays a crucial role in controlling cell proliferation, making it an excellent target for cancer therapy. In this work, a set of small molecules were identified as Cdc25 modulators by applying a mixed ligand-structure-based approach and taking advant...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Lauria, Antonino, Martorana, Annamaria, La Monica, Gabriele, Mannino, Salvatore, Mannino, Giuseppe, Peri, Daniele, Gentile, Carla
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8038176/
https://ncbi.nlm.nih.gov/pubmed/33918281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073714
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