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A Comprehensive Review of Genetically Engineered Mouse Models for Prader-Willi Syndrome Research

Prader-Willi syndrome (PWS) is a neurogenetic multifactorial disorder caused by the deletion or inactivation of paternally imprinted genes on human chromosome 15q11-q13. The affected homologous locus is on mouse chromosome 7C. The positional conservation and organization of genes including the impri...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kummerfeld, Delf-Magnus, Raabe, Carsten A., Brosius, Juergen, Mo, Dingding, Skryabin, Boris V., Rozhdestvensky, Timofey S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037846/
https://ncbi.nlm.nih.gov/pubmed/33807162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073613
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