Ectopic expression of Snord115 in choroid plexus interferes with editing but not splicing of 5-Ht2c receptor pre-mRNA in mice

Serotonin 5-HT2C receptor is a G-protein coupled excitatory receptor that regulates several biochemical pathways and has been implicated in obesity, mental state, sleep cycles, autism, neuropsychiatric disorders and neurodegenerative diseases. The activity of 5-HT2CR is regulated via alternative spl...

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Publicat a:Sci Rep
Autors principals: Raabe, Carsten A., Voss, Reinhard, Kummerfeld, Delf-Magnus, Brosius, Juergen, Galiveti, Chenna R., Wolters, Anna, Seggewiss, Jochen, Huge, Andreas, Skryabin, Boris V., Rozhdestvensky, Timofey S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414643/
https://ncbi.nlm.nih.gov/pubmed/30862860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39940-6
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