Elucidation of the Clustered Nano-Architecture of Radiation-Induced DNA Damage Sites and Surrounding Chromatin in Cancer Cells: A Single Molecule Localization Microscopy Approach

In cancer therapy, the application of (fractionated) harsh radiation treatment is state of the art for many types of tumors. However, ionizing radiation is a “double-edged sword”—it can kill the tumor but can also promote the selection of radioresistant tumor cell clones or even initiate carcinogene...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Hausmann, Michael, Falk, Martin, Neitzel, Charlotte, Hofmann, Andreas, Biswas, Abin, Gier, Theresa, Falkova, Iva, Heermann, Dieter W., Hildenbrand, Georg
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037797/
https://ncbi.nlm.nih.gov/pubmed/33807337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073636
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