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Osmolality Effects on CHO Cell Growth, Cell Volume, Antibody Productivity and Glycosylation
The addition of nutrients and accumulation of metabolites in a fed-batch culture of Chinese hamster ovary (CHO) cells leads to an increase in extracellular osmolality in late stage culture. Herein, we explore the effect of osmolality on CHO cell growth, specific monoclonal antibody (mAb) productivit...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8037477/ https://ncbi.nlm.nih.gov/pubmed/33804825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073290 |
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