The Agonist Action of Alkylphenols on TRPA1 Relates to Their Effects on Membrane Lipid Order: Implications for TRPA1-Mediated Chemosensation

The Transient Receptor Potential Ankyrin 1 cation channel (TRPA1) is a broadly-tuned chemosensor expressed in nociceptive neurons. Multiple TRPA1 agonists are chemically unrelated non-electrophilic compounds, for which the mechanisms of channel activation remain unknown. Here, we assess the hypothes...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Startek, Justyna B., Milici, Alina, Naert, Robbe, Segal, Andrei, Alpizar, Yeranddy A., Voets, Thomas, Talavera, Karel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037438/
https://ncbi.nlm.nih.gov/pubmed/33806007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073368
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