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A Highly Selective In Vitro JNK3 Inhibitor, FMU200, Restores Mitochondrial Membrane Potential and Reduces Oxidative Stress and Apoptosis in SH-SY5Y Cells

Current treatments for neurodegenerative diseases (ND) are symptomatic and do not affect disease progression. Slowing this progression remains a crucial unmet need for patients and their families. c-Jun N-terminal kinase 3 (JNK3) are related to several ND hallmarks including apoptosis, oxidative str...

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Publicat a:Int J Mol Sci
Autors principals: Rehfeldt, Stephanie Cristine Hepp, Laufer, Stefan, Goettert, Márcia Inês
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037381/
https://ncbi.nlm.nih.gov/pubmed/33918172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073701
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