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Protonation Equilibrium in the Active Site of the Photoactive Yellow Protein

The role and existence of low-barrier hydrogen bonds (LBHBs) in enzymatic and protein activity has been largely debated. An interesting case is that of the photoactive yellow protein (PYP). In this protein, two short HBs adjacent to the chromophore, p-coumaric acid (pCA), have been identified by X-r...

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Pubblicato in:Molecules
Autori principali: Campomanes, Pablo, Vanni, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037372/
https://ncbi.nlm.nih.gov/pubmed/33918211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26072025
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