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Protonation Equilibrium in the Active Site of the Photoactive Yellow Protein

The role and existence of low-barrier hydrogen bonds (LBHBs) in enzymatic and protein activity has been largely debated. An interesting case is that of the photoactive yellow protein (PYP). In this protein, two short HBs adjacent to the chromophore, p-coumaric acid (pCA), have been identified by X-r...

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Publicat a:Molecules
Autors principals: Campomanes, Pablo, Vanni, Stefano
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037372/
https://ncbi.nlm.nih.gov/pubmed/33918211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26072025
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