Cytotoxic Activity of LLO Y406A Is Targeted to the Plasma Membrane of Cancer Urothelial Cells

Identification of novel agents for bladder cancer treatment is highly desirable due to the high incidence of tumor recurrence and the risk of progression to muscle-invasive disease. The key feature of the cholesterol-dependent toxin listeriolysin O mutant (LLO Y406A) is its preferential activity at...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Resnik, Nataša, Tratnjek, Larisa, Kreft, Mateja Erdani, Kisovec, Matic, Aden, Saša, Bedina Zavec, Apolonija, Anderluh, Gregor, Podobnik, Marjetka, Veranič, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037347/
https://ncbi.nlm.nih.gov/pubmed/33805017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073305
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