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Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease

Alzheimer’s disease affects millions of lives worldwide. This terminal disease is characterized by the formation of amyloid aggregates, so-called amyloid oligomers. These oligomers are composed of β-sheet structures, which are believed to be neurotoxic. However, the actual secondary structure that c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Paulus, Agnes, Engdahl, Anders, Yang, Yiyi, Boza-Serrano, Antonio, Bachiller, Sara, Torres-Garcia, Laura, Svanbergsson, Alexander, Garcia, Megg G., Gouras, Gunnar K., Li, Jia-Yi, Deierborg, Tomas, Klementieva, Oxana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037084/
https://ncbi.nlm.nih.gov/pubmed/33810433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073430
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