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Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease

Alzheimer’s disease affects millions of lives worldwide. This terminal disease is characterized by the formation of amyloid aggregates, so-called amyloid oligomers. These oligomers are composed of β-sheet structures, which are believed to be neurotoxic. However, the actual secondary structure that c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Paulus, Agnes, Engdahl, Anders, Yang, Yiyi, Boza-Serrano, Antonio, Bachiller, Sara, Torres-Garcia, Laura, Svanbergsson, Alexander, Garcia, Megg G., Gouras, Gunnar K., Li, Jia-Yi, Deierborg, Tomas, Klementieva, Oxana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037084/
https://ncbi.nlm.nih.gov/pubmed/33810433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073430
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