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Hypoxia-Induced Alpha-Globin Expression in Syncytiotrophoblasts Mimics the Pattern Observed in Preeclamptic Placentas

Preeclampsia (PE) is a pregnancy disorder associated with placental dysfunction and elevated fetal hemoglobin (HbF). Early in pregnancy the placenta harbors hematopoietic stem and progenitor cells (HSPCs) and is an extramedullary source of erythropoiesis. However, globin expression is not unique to...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Masoumi, Zahra, Erlandsson, Lena, Hansson, Eva, Magnusson, Mattias, Mezey, Eva, Hansson, Stefan R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036899/
https://ncbi.nlm.nih.gov/pubmed/33806017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073357
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