Syncytiotrophoblast Vesicles Show Altered micro-RNA and Haemoglobin Content after Ex-vivo Perfusion of Placentas with Haemoglobin to Mimic Preeclampsia

BACKGROUND: Cell-free foetal haemoglobin (HbF) has been shown to play a role in the pathology of preeclampsia (PE). In the present study, we aimed to further characterize the harmful effects of extracellular free haemoglobin (Hb) on the placenta. In particular, we investigated whether cell-free Hb a...

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Detalhes bibliográficos
Main Authors: Cronqvist, Tina, Saljé, Karen, Familari, Mary, Guller, Seth, Schneider, Henning, Gardiner, Chris, Sargent, Ian L., Redman, Christopher W., Mörgelin, Matthias, Åkerström, Bo, Gram, Magnus, Hansson, Stefan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937405/
https://ncbi.nlm.nih.gov/pubmed/24587192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090020
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