Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus

Adenoviruses contain dsDNA covalently linked to a terminal protein (TP) at the 5′end. TP plays a pivotal role in replication and long-lasting infectivity. TP has been reported to contain a nuclear localisation signal (NLS) that facilitates its import into the nucleus. We studied the potential NLS mo...

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Pubblicato in:Int J Mol Sci
Autori principali: Al-Wassiti, Hareth A., Thomas, David R., Wagstaff, Kylie M., Fabb, Stewart A., Jans, David A., Johnston, Angus P., Pouton, Colin W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036708/
https://ncbi.nlm.nih.gov/pubmed/33804953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073310
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