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Interleukin-13 Propagates Prothrombin Kringle-2-Induced Neurotoxicity in Hippocampi In Vivo via Oxidative Stress

The present study investigated expression of endogenous interleukin-13 (IL-13) and its possible function in the hippocampus of prothrombin kringle-2 (pKr-2)-lesioned rats. Here we report that intrahippocampal injection of pKr-2 revealed a significant loss of NeuN-immunopositive (NeuN(+)) and Nissl(+...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jeong, Jae Yeong, Wi, Rayul, Chung, Young Cheul, Jin, Byung Kwan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036367/
https://ncbi.nlm.nih.gov/pubmed/33801783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073486
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