Targeting Replicative Stress and DNA Repair by Combining PARP and Wee1 Kinase Inhibitors Is Synergistic in Triple Negative Breast Cancers with Cyclin E or BRCA1 Alteration

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) is a subtype of invasive breast cancer with an aggressive phenotype that has decreased survival compared with other types of breast cancers, due in part to the lack of biomarker driven targeted therapies. Here, we show that breast cancer patients...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancers (Basel)
Päätekijät: Chen, Xian, Yang, Dong, Carey, Jason P. W., Karakas, Cansu, Albarracin, Constance, Sahin, Aysegul A., Arun, Banu K., Guray Durak, Merih, Li, Mi, Kohansal, Mehrnoosh, Bui, Tuyen N., Ha, Min-Jin, Hunt, Kelly K., Keyomarsi, Khandan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8036262/
https://ncbi.nlm.nih.gov/pubmed/33916118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071656
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia