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Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts

Single-cell RNA sequencing (scRNA-seq) provides a powerful tool to determine expression patterns of thousands of individual cells. However, the analysis of scRNA-seq data remains a computational challenge due to the high technical noise such as the presence of dropout events that lead to a large pro...

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Bibliografiska uppgifter
I publikationen:J Mol Cell Biol
Huvudupphovsmän: Zhang, Lihua, Zhang, Shihua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035992/
https://ncbi.nlm.nih.gov/pubmed/33002136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjaa052
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