Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In Mouse

Significance: Red blood cell (RBC)-mediated vasodilation plays an important role in oxygen delivery. This occurs through hemoglobin actions, at least in significant part, to convert heme-bound nitric oxide (NO) (in tense [T]/deoxygenated-state hemoglobin) into vasodilator S-nitrosothiol (SNO) (in re...

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Bibliographische Detailangaben
Veröffentlicht in:Antioxid Redox Signal
Hauptverfasser: Premont, Richard T., Reynolds, James D., Zhang, Rongli, Stamler, Jonathan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2021
Schlagworte:
Redox and Nitrosative Signaling in the Vasculature (Ed. Gabor Csanyi)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035927/
https://ncbi.nlm.nih.gov/pubmed/32597195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2020.8153
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