Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene-environment interaction study

BACKGROUND: In contrast to most other common diseases, few genetic variants have been identified that impact risk of cirrhosis. We aimed to identify new genetic variants that predispose to cirrhosis, to test whether such variants, aggregated into a polygenic score, enable genomic risk stratification...

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Vydáno v:Gastroenterology
Hlavní autoři: Emdin, Connor A, Haas, Mary, Ajmera, Veeral, Simon, Tracey G, Homburger, Julian, Neben, Cynthia, Jiang, Lan, Wei, Wei-Qi, Feng, Qiping, Zhou, Alicia, Denny, Joshua, Corey, Kathleen, Loomba, Rohit, Kathiresan, Sekar, Khera, Amit V
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035329/
https://ncbi.nlm.nih.gov/pubmed/33310085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.12.011
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