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N-Acetyl-l-cysteine and aminooxyacetic acid differentially modulate trichloroethylene reproductive toxicity via metabolism in Wistar rats

Exposure to the industrial solvent trichloroethylene (TCE) has been associated with adverse pregnancy outcomes in humans and decreased fetal weight in rats. TCE kidney toxicity can occur through formation of reactive metabolites via its glutathione (GSH) conjugation metabolic pathway, largely unstud...

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Библиографические подробности
Опубликовано в: :Arch Toxicol
Главные авторы: Su, Anthony L., Lash, Lawrence H., Bergin, Ingrid L., Bjork, Faith, Loch-Caruso, Rita
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035313/
https://ncbi.nlm.nih.gov/pubmed/33599830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-02991-8
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